The peripheral nerves and blood vessels involve in the process of the rumor development and form pathological loci of the pain, which is especially frequent after the surgical intervention. Hence, pain management becomes the key component of the life quality of the cancer patient. The Clinic provides all types of pain management including superpotent psychotropic, narcotic and non-narcotic substances, transdermal pain killing patches and all types of nerve block anesthesia. The intensive care unit provides pain management 24/7. In case of the bone metastases the pain can be managed by the low doses of focused ionizing radiation, as well as the range of contemporary pain killers and nerve block anesthesia.